CARBOXYLASES OF ANIMAL TISSUES

Plant biotin-containing carboxylases.

Biotin-containing proteins are found in all forms of life, and they catalyze carboxylation, decarboxylation, or transcarboxylation reactions that are central to metabolism. In plants, five biotin-containing proteins have been characterized. Of these, four are catalysts, namely the two structurally distinct acetyl-CoA carboxylases (heteromeric and homomeric), 3-methylcrotonyl-CoA carboxylase and...

Formate Metabolism by Animal Tissues*?

Many studies on the metabolism of formic acid by a variety of animal tissues have shown that an appreciable portion of this substrate is oxidized to carbon dioxide (6-13). Since the initial observation of Battelli (6) and Battelli and Stern (7) on the oxidation in vitro of formate, various uncorrelated attempts have been made to identify the responsible enzymes to explain the mechanism of this ...

Phosphorus Compounds in Animal Tissues

The concept that nucleic acids are intimately associated with fundamental cellular processes has gained considerable favor within the last few years. This can undoubtedly be attributed to the researches of Caspersson and his associates. Caspersson, with the aid of ultraviolet spectrophotometry, has been able to measure the nucleic acids in various parts of the cell under a variety of experiment...

Deoxyribosyl compounds in animal tissues.

Several types of deoxyribosyl compounds have been found in the acidsoluble fraction of normal and malignant tissues (l-8). In 1955 Potter and Schlesinger (1) reported the isolation of deoxynucleoside mono-, di-, and triphosphates from extracts of calf thymus. More recently LePage (7) reported the isolation of deoxyadenosine triphosphate from a tumor. Schneider (2), using a microbiological assay...

Drug residues in animal tissues.